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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3
All Species:
20
Human Site:
T129
Identified Species:
44
UniProt:
P19429
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19429
NP_000354.4
210
24008
T129
I
T
E
I
A
D
L
T
Q
K
I
F
D
L
R
Chimpanzee
Pan troglodytes
XP_001134934
215
23988
V136
C
R
Q
L
H
A
R
V
D
K
V
D
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001085820
210
23930
T129
I
T
E
I
A
D
L
T
Q
K
I
F
D
L
R
Dog
Lupus familis
XP_851068
182
21393
N97
T
K
E
L
E
D
M
N
Q
K
L
F
D
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P48787
211
24240
T130
I
T
E
I
A
D
L
T
Q
K
I
Y
D
L
R
Rat
Rattus norvegicus
P23693
211
24141
T130
I
T
E
I
A
D
L
T
Q
K
I
Y
D
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P68246
183
21216
S97
N
K
E
L
E
D
L
S
Q
K
L
F
D
L
R
Frog
Xenopus laevis
P50754
244
28179
N154
I
T
E
L
E
D
L
N
Q
K
I
F
D
L
R
Zebra Danio
Brachydanio rerio
NP_001008613
182
21013
N98
T
R
E
I
K
D
L
N
I
K
V
L
D
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36188
269
30063
N189
D
W
E
I
N
D
L
N
A
Q
V
N
D
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9GYF1
242
27542
T131
E
A
E
I
N
S
L
T
I
E
V
N
D
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.1
98
53.8
N.A.
92.4
92.4
N.A.
N.A.
53.3
63.1
54.7
N.A.
29
N.A.
22.7
N.A.
Protein Similarity:
100
84.6
98.5
68.5
N.A.
95.2
95.2
N.A.
N.A.
69
74.1
70
N.A.
46.4
N.A.
47.9
N.A.
P-Site Identity:
100
13.3
100
53.3
N.A.
93.3
93.3
N.A.
N.A.
60
80
53.3
N.A.
46.6
N.A.
46.6
N.A.
P-Site Similarity:
100
40
100
73.3
N.A.
100
100
N.A.
N.A.
80
86.6
60
N.A.
60
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
37
10
0
0
10
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
82
0
0
10
0
0
10
91
0
0
% D
% Glu:
10
0
91
0
28
0
0
0
0
10
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
46
0
0
64
0
0
0
0
19
0
46
0
0
0
0
% I
% Lys:
0
19
0
0
10
0
0
0
0
82
0
0
0
0
0
% K
% Leu:
0
0
0
37
0
0
82
0
0
0
19
10
0
91
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
19
0
0
37
0
0
0
19
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
64
10
0
0
0
0
0
% Q
% Arg:
0
19
0
0
0
0
10
0
0
0
0
0
0
0
100
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% S
% Thr:
19
46
0
0
0
0
0
46
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
37
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _